What is celiac disease?
Celiac disease is gluten intolerance. In people with such intolerance, the action of gluten develops an autoimmune inflammation of the small intestine mucosa, which leads to the destruction of mucous villi and microvilli. As a result, the surface of the small intestine shrinks, reducing its ability to digest and absorb nutrients. Due to malabsorption of nutrients, metabolism can be impaired.
Typical symptoms of celiac disease are diarrhea, flatulence, abdominal cramps, weight loss, and fatigue.
This disorder can occur at any age – in childhood or adulthood. Celiac disease is treated with a gluten-free diet.
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How can CBD be effective in treating celiac disease?
CBD is a natural compound derived from the Cannabis Sativa hemp plant. CBD effectively integrates with the human endocannabinoid system – this system consists of endocannabinoids, as well as cannabinoid receptors CB1 and CB2, which regulate bodily functions such as immunity, sleep, appetite, pain, and mood.
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CBD triggers the production of CB1 and CB2 and boosts the body's immune system. It may also help relieve symptoms of celiac disease such as pain, inflammation, loss of appetite, and irritation that affect the gastrointestinal tract.
Some patients also complain of nausea, which can lead to anorexia and weight loss. CBD has a positive effect on nausea and regulates appetite.
CBD has been scientifically proven to be an inhibitor of the enzyme FAAH, also known as fatty acid amide hydrolase. CBD may be a solution to neuropathic pain (diabetic neuropathy is a nerve lesion most often manifested by pain, lower limb spasms) as it has neuroprotective and neurodegenerative properties.
How to Use CBD to Treat Celiac Disease
CBD can be used in a variety of ways and in a variety of forms. Patients usually prefer products such as CBD oil, CBD coconut oil, or CBD capsules.
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However, the vaporization method is also effective - it speeds up absorption and speeds up the relief of unpleasant symptoms of celiac disease.
How to properly dose CBD
Several factors must be considered before starting to take it. This may include the severity/phase of your condition as well as how well your body tolerates CBD.
To find the ideal dose of CBD for your particular occasion, you may need to experiment a bit and look for signs of improvement. An excellent guide to dosing CBD is the gradual increase method developed by Lainow and Birnbaum in their book CBD: A Guide to Medical Cannabis for Patients. The authors recommend starting at a lower dose and gradually increasing it until symptoms improve.
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Medical research on the use of CBD in celiac disease
While we are looking into the possible effects of CBD on a condition called celiac disease, we must acknowledge that only limited research has focused on this topic.
For example, in 2011, in the scientific journal PLOS One, studies were conducted by Italian scientists who decided to evaluate the possibility of reducing intestinal inflammation after using CBD for celiac disease. As a result, it prevents intestinal damage, a symptom associated with this disease.
However, more research needs to be done to explore the therapeutic effects of CBD in alleviating the symptoms of celiac disease.